Sal e Pepe cares about our community. Sal e Pepe believes in supporting the organizations and causes within our own local areas that give us so many opportunities for growth and development.

In addition, we are
proud to support the
Rett Syndrome Research Trust, a nonprofit research organization formed in the wake of the dramatic pre-clinical reversal of Rett Syndrome symptoms.

Sal e Pepe is proud to support the efforts of the Rett Syndrome Research Trust. In 1998 my niece was diagnosed with Rett Syndrome, the most physically disabling of the autism spectrum disorders. Rett Syndrome strikes little girls almost exclusively, with first symptoms usually appearing before the age of 18 months. These children lose speech, motor control and functional hand use, and many suffer from seizures, orthopedic and severe digestive problems, breathing and other autonomic impairments. Most live into adulthood, and require total, round-the-clock care.

Unexpectedly, these severe symptoms have been shown to be reversible in pre-clinical models. The Rett Syndrome Research Trust is a nonprofit research organization formed by my sister in the wake of the reversal. The Trust is intensively focused on the development of treatments and cures for Rett Syndrome and related MECP2 disorders. To learn more about the Trust please visit www.reverserett.org.